Seok-Cheol Hong

Seok-Cheol Hong

Citizenship: Korea

Work address: Department of Physics

Asan Science Hall, Rm 402 &

CMSD, IBS, KU-R&D Center, Rm 115, Korea University,

Anam, Seongbuk, Seoul, Korea, 02841

Tel: +82-2-3290-3112

Cell: +82-10-2265-4187

E-mail: hongsc@korea.ac.kr; hong1sc@gmail.com

Homepage: http://biophys.korea.ac.kr

Education

l September 1996 - June 2002:

Ph.D. in Physics, University of California at Berkeley (Supervisor: Dr. Yuen-Ron Shen)

Ph.D. research: “Nonlinear Optical Studies of Liquid Crystals and Polymers”

l September 1995 - May 1996:

Department of Physics, University of Pennsylvania

l March 1992 - August 1995:

Undergraduate Degree (Summa Cum Laude) in Physics, Seoul National University

Employment & Affiliation

l January 2020 – Present:

Affiliate Professor in Computational Sciences in KIAS, Seoul, Korea

l March 2018 – February 2019:

Visiting Professor in Computational Sciences in KIAS, Seoul, Korea

l January 2015 – Present:

Collaborator (Team IV: Single-molecule Imaging/Label-free Imaging) in Center for Molecular

Spectroscopy and Dynamics (CMSD), Institute for Basic Science (IBS), Seoul, Korea

l March 2014 – Present:

Professor in Department of Physics in Korea University, Seoul, Korea

l March 2013 – February 2018:

Affiliate Professor in Computational Sciences in KIAS, Seoul, Korea

l January 2011 – February 2012:

Visiting Professor in Computational Sciences in KIAS, Seoul, Korea

l September 2008 – February 2014:

Associate Professor in Department of Physics in Korea University, Seoul, Korea.

l September 2004 – August 2008:

Assistant Professor in Department of Physics in Korea University, Seoul, Korea.

l August 2002 – July 2004:

Postdoctoral researcher in Prof. Nicholas R. Cozzarelli's group and Carlos Bustamante's group in

University of California at Berkeley

l June 1997 - June 2002:

Research Assistant in Prof. Yuen-Ron Shen’s group in University of California at Berkeley

l September 1996 - December 1996:

Teaching Assistant in Introductory Physics Lab. in University of California at Berkeley

Honor & Awards

* Yong-Bong Prize (용봉상) from Division of Statistical Physics of Korean Physical

Society (2013)

* Seok-Top Best Teaching Award (석탑강의상) from Korea University (2020-2)

Service

* College of Science, Korea University

- Vice Dean (부학장): Mar. 2022 – Feb. 2024

* Korean Physical Society

-Vice secretary of Editorial Board – “Physics & Advanced Technology” (홍보잡지부실무이사): Jan. 2011 – Dec. 2012

- Secretary of Education Committee (Physics Certificate: 물리인증제 학력평가이사):

Jan. 2013 – Dec. 2014:

- Secretary of Education Committee (Popularization of Physics: 대중화사업이사): Jan.

2019 – Dec. 2020

- Secretary of Education Committee (Educational Evaluation: 학력평가실무이사): Jan.

2021 – Dec. 2022

- Secretary of ad hoc (Special) Committee for Funding Program (연구비전특별위원회간사 및 생물물리분과 추천위원): Jan. 2021 – Dec. 2022

*KPS Division Committee member

- Biological Physics Div.

- Inaugural Secretary of Scholarly Program (학술간사): Jan. 2019 – Apr. 2021

- Statistical Physics Div.: committee member (in the past)

- Applied Physics Div.: committee member (in the past)

* ICAMD (International Conference on Advanced Materials and Devices) Program committee member: 2005, 2007, 2009, 2011, 2013, 2015, 2017

* ICBP2023 (International Conference on Biological Physics 2023) Program committee member Editorial Board Member

Scientific Report: Apr. 2015 ~

Frontiers in Bioengineering and Biotechnology: Jun. 2015 ~

Current Applied Physics: Mar. 2016 ~

Publication

* S. E. Kim et al, Two opposing effects of monovalent cations on the stability of i-motif structure. Under review in J. Phys. Chem. B.

* K. Zambochova et al, Axial Profiling of Interferometric Scattering Enables an Accurate Determination of Nanoparticle Size. Under review in Optics Express.

* C. J. Park et. al, Two-Color Infrared Photothermal Microscopy. Under revision in Chemical Science.

* J. S. Park et al, Long-term cargo tracking reveals intricate trafficking through active cytoskeletal networks in the crowded cellular environment. Under revision in Nat. Comm.

* H.-M. Moon et al, Cisplatin fastens chromatin irreversibly even at a high chlorideconcentration. Nucleic Acids Res. (2021) DOI: 10.1093/nar/gkab922

* S. Kim, et al, Z-DNA as a Tool for Nuclease-Free DNA Methyltransferase Assay. Int. J. Mol. Sci. 2021, 22(21), 11990; https://doi.org/10.3390/ijms222111990

* E. Lerner et al, FRET-based dynamic structural biology: challenges, perspectives and an appeal for open-science practices. eLife. (2021) 10:e60416 DOI:10.7554/eLife.60416.

* S. Kim et al, Sequence-dependent cost for Z-form shapes the torsion-driven B-Z transition via close interplay of Z-DNA and bubble. Nucleic Acids Res. (2021) DOI: 10.1093/nar/gkab153

* J. S. Park et al, Fluorescence-combined interferometric scattering imaging reveals nanoscale dynamic events of single nascent adhesions in living cells. J. Phys. Chem. Lett. (2020) DOI: 10.1021/acs.jpclett.0c02103

* I.-B. Lee et al, Three-dimensional interferometric scattering microscopy via remote focusing technique. Optics Letters. 45, 2628-2631 (2020) DOI: 10.1364/OL.386172

* S. Kim et al, Unveiling the pathway to Z-DNA in the protein-induced B-Z transition. Nucleic Acids Res. (2018) DOI: 10.1093/nar/gky200

* J. S. Park et al, Label-free and live cell imaging by interferometric scattering microscopy. Chemical Sciences (2018) DOI: 10.1039/c7sc04733a

* I. B. Lee, et al, Interferometric Scattering Microscopy with Polarization-Selective Dual Detection Scheme: Capturing the Orientational Information of Anisotropic Nanometric Objects. ACS Photonics (2017) DOI: 10.1021/acsphotonics.7b00890

* W. Hwang, et al, Decoding Single Molecule Time Traces with Dynamic Disorder. PLoS Comput. Biol. (2016) vol.12 e1005286.

* A.-Y. Kwon, et al, Competition between B-Z and B-L transitions in a single DNA molecule: Computational studies. Phys. Rev. E (2016) vol 93, 022411.

* S.-C. Hong, et al, Bridging Moments of Inertia Between Solids and Shells: Go from Known to the Unknown! Resonance, August (2015).

* S. E. Kim, et al, Deciphering Kinetic Information from Single-Molecule FRET Data That Show Slow Transitions. J. Phys. Chem. B (2015) vol. 119, 6974.

* A.-Y. Kwon, et al, Annealed Random Copolymer Model of the B-Z Transition in DNA: Torsional Responses. Biophys. J. (2015) vol. 108, 2562.

* S. E. Kim, et al, Destabilization of i-Motif by Submolar Concentrations of a Monovalent Cation, J. Phys. Chem. B (2014) vol. 118, 4753.

* S. I. Hong, et al, Moments of inertia of spheres without integration in arbitrary dimensions, Eur. J. Phys. (2014) vol. 35, 025003.

*N.-K. Lee et al. Underwound DNA under tension: L-DNA vs. Plectoneme. Eur. Phys. L (2014) vol. 105, 48002.

*S. I. Hong, et al, The torque landscapes of a Johnson electric motor, Physics Education (2013), 709.

*N.-K. Lee et al. DNA triplex folding: moderate versus high salt conditions. Eur. Phys. J. E. (2013) vol. 36, 57.

*S.-C. Hong et al. Moments of Inertia of Disks and Spheres Without Integration. Phys. Teach. (2013) vol 51, 139.

*I. B. Lee et al. Kinetics of the Triplex-Duplex Transition in DNA. Biophys. J. (2012) vol. 103 pp 2492-2501. (Featured on Cover)

*J.-S. Park et al. In situ analysis of cisplatin binding to DNA: the effects of physiological ionic conditions. Phys. Chem. Chem. Phys. (2011) vol. 14 pp. 3128-33.

*M. Lee et al. Minute negative superhelicity is sufficient to induce the B-Z transition in the presence of low tension. Proceedings of the National Academy of Sciences (PNAS) (2010) vol.107 (11) pp. 4985-4990

*N.-K. Lee et al. Investigation of the elasticity of a cisplatin-DNA adduct via single-molecule measurements and bimodal modeling. Phys. Rev. E (2009) vol. 79 pp. 041921

*S. I. Hong, et al, Making a Simple Self-Starting Electric Motor. The Physics Teachers (2009) vol. 47 pp. 204-205

*N.-K. Lee et al. Elasticity of cisplatin-bound DNA reveals the degree of cisplatin binding. Physical Review Letters (2008) vol. 101 (24) pp. 248101

*H. Kim et al. Two-photon fluorescent turn-on probe for lipid rafts in live cell and tissue. J. Am. Chem. Soc (2008) vol. 130 (13) pp. 4246-7

*H. Kim et al. Two-photon fluorescent probes for acidic vesicles in live cells and tissue. ANGEWANDTE CHEMIE International Edition (2008) vol. 47 (12) pp. 2231-4

*M. Nöllmann et al. Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque. Nat. Struct. Mol. Biol (2007) vol. 14 (4) pp. 264-71

*N.-K. Lee, et al. Compressing a rigid filament: Buckling and cyclization (2007) Eur. Phys. J. E. 24 : 229-241.

*P. G. Gucciardi et al, Artifacts identification in apertureless near-field optical microscopy J. Appl. Phys. (2007) 101:064303

Patents

* 홍석철, 김숙호, DNA 메틸화 저해 약물 스크리닝 방법, 국내특허 등록번호, 10-2316832 (2021).