Jong-Bong Lee

Jong-Bong Lee, Ph.D

Professor of Physics/ School of Interdisciplinary Bioscience & Bioengineering (IBIO) POSTECH

77 Cheongam-Ro, Nam-gu

Pohang-si 37673, Korea

Phone: 82-54-279-2095

E-mail: jblee@postech.ac.kr

Lab homepage: jblab.postech.ac.kr

A. Education

• 2004: Ph.D. Physics, Brandeis University, MA, USA

• 1996: MS, Physics, Sogang University, Korea

• 1993: BS, Physics in major and Mathematics in minor, Sogang University, Korea

B. Professional Experience

• 2021 ~ 2022: Visiting Professor, Department of Chemistry, Rice University, Houston, TX, USA

• 2019 ~ 2021: Head Professor, IBIO, POSTECH, Pohang, Korea

• 2019 ~ 2021: Chair, Division of Biological Physics, the Korean Physical Society

• 2017 ~ 2019: Review Board, National Research Foundation of Korea

• 2017 ~ 2019: Mueunjae-Chaired Professor

• 2013 ~ 2014: Visiting Professor, Department of Cancer Biology and Genetics, College of Medicine, Ohio State University, Columbus, OH, USA

• 2007 ~ Present: Assistant, Associate, and Full Professor, Department of Physics and School of Interdisciplinary Bioscience & Bioengineering (IBIO), POSTECH, Korea

• 2004 ~ 2007: Postdoctoral Research, Harvard Medical School, Boston, MA, USA C. Honors & Awards

• 2019: LG Yonam Academic Support for professors’ overseas research

• 2017: Fundamental Science Excellence awarded by the Ministry of Science and ICT of Korea

• 2017: Proud POSTECHIAN, Excellence in Research, awarded by POSTECH

• 2017: National R&D Excellence 100 awarded by the Korean Government

• 2017: Mueunjae-Chaired Professor awarded by POSTECH

• 2016: The 23rd Samsung HumanTech Paper Award, Gold prize (Adviser)

• 2012: The 19th Samsung HumanTech Paper Award, Silver prize (Adviser)

D. Selected Publications

# co-first authors, * Corresponding authors

o M. Chang#, O.C. Lee#, G. Bu#, J. Oh, N.-O. Yunn, S. H. Ryu, H.-B. Kwon, A.B. Kolomeisky, S.-H. Shim, J. Doh, J.-H. Jeon*, J.-B. Lee*, “Formation of cellular close-ended tunneling nanotubes through mechanical deformation.” Science Advances 8, eabj3995 (2022)

o J. London#, J. Martín-López#, I. Yang#, J. Liu, J.-B. Lee*, R. Fishel*, “Linker domain function predicts pathogenic MLH1 missense variants.” Proc. Natl. Acad. Sci. USA 118 (9), e2019215118 (2021)

o Y. Park#, J. Park#, H.J. Hwang#, B. Kim#, K. Jeong, J. Chang, J.-B. Lee*, Y.K. Kim*, “Nonsensemediated mRNA decay factor UPF1 promotes aggresome formation” Nature Communications, 11, 3106 (2020)

o J. Liu#, R. Lee#, B. Britton#, J. London, K. Yang, J. Hanne, J, J.-B. Lee*, R. Fishel*, “MutL sliding clamps coordinate exonuclease-independent Escherichia coli mismatch repair” Nature Communications, 10, 5294 (2019)

o D. Kim, F. Rashid, Y. Cho, M.S. Zaher, I.H. Cho, S. Hamdan, C. Jeong*, J.-B. Lee*, “DNA skybridge: 3D structure producing a light sheet for high-throughput single-molecule imaging” Nucleic Acids Research 47, e107 (2019)

o J. Liu#, J. Hanne#, B.M. Britton, J. Bennett, D. Kim, J.-B. Lee*, R. Fishel*, “Cascading MutS and MutL sliding clamps control DNA diffusion to activate mismatch repair” Nature 539, 583 (2016).

o Y. Jeon, D. Kim, J.V. Martín-López, R. Lee, J. Oh, J. Hanne, R. Fishel* and J.-B. Lee*, “Dynamic control of strand excision during human DNA mismatch repair” Proc. Natl. Acad. Sci. USA 113, 3281 (2016).

o W.K. Cho, S. Jergic, D. Kim, N. Dixon, J.-B. Lee*, “Loading Dynamics of a sliding DNA Clamp” Angewandte Chemie-Int. Edit. 53, 6788 (2014).

o S.H. Lee, J. Oh, J. Park, K.Y. Paek, S. Rho, S.K. Jang*, J.-B. Lee*, “Poly(A) RNA and Paip2 Act as Allosteric Regulators of Poly(A)-Binding Protein” Nucleic Acids Research 42, 2697 (2014).

o S. Lee, J. Oh, D. Kim, S. Kim, J.-B. Lee*, H.G. Nam*, “Polarization-controlled Photo-switching Reveals Directions with Sub-wavelength Resolution” Physical Review Letters 109, 248101 (2012).

o C. Jeong#, W.-K. Cho#, K.-M. Song, C. Cook, T.-Y. Yoon, C. Ban*, R. Fishel*, J.-B. Lee*, “MutS Switches Between Two Fundamentally Distinct Clamps during Mismatch Repair” Nature Structural & Molecular Biology 18, 379-385 (2011).

o J.-B. Lee, R.K. Hite, S.M. Hamdan, X.S. Xie, C.C. Richardson, A.M. van Oijen*, “DNA primase acts as a molecular brake in DNA replication” Nature 439, 621-624 (2006).